Furosemide: Indications

Furosemide still flushes out edema when other drugs fail. It is thus suitable for the diuretic treatment of chronic heart failure and it is the drug of choice for acute pulmonary edema. For impaired renal functions (e.g.diabetes patients) and for nephrotic syndrome, loop diuretics are often the only drugs that can flush out massive edema. High doses of furosemide may reduce the necessity of dialysis for acute renal failure but they do not decrease total mortality. Furosemide complements the effect of spironolactone for edema caused by hepatic cirrhoses. If furosemide is still insufficiently effective, a combination with metolazone can be considered. These intensive therapies are accompanied by high risks of dangerous electrolyte imbalances!

Furosemide as a single drug is only exceptionally indicated for the treatment of hypertension, but it can very well be combined with other antihypertensive agents, e.g. when thiazide diuretics are not adequate. Loop diuretics are also efficacious on hypercalcemia. As an aerosol for allergic asthma, furosemide acts as a bronchodilator; for the time being, however, such preparations are not available.

Table of Contents | Pharmacology | Adverse Reactions & Interactions | Contraindications & Cautions | Risk Groups | References